Ancient chicken remains reveal the origins of virulence in Marek’s disease (Registre núm. 39093)
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| 000 -LEADER | |
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| fixed length control field | 01468nab a22002177a 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20231221180144.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 231218b2023 ||||| |||| 00| 0 eng d |
| 041 ## - LANGUAGE CODE | |
| Idioma del document | Anglès |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 25786 |
| Personal name | Fiddaman, Steven R. |
| 245 ## - TITLE STATEMENT | |
| Títol | Ancient chicken remains reveal the origins of virulence in Marek’s disease |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Marek’s disease virus (MDV) causes tumors in chickens and has increased in virulence over the past century. Fiddaman et al. studied ancient DNA from chickens to reveal the evolutionary history of this once mild disease (see the Perspective by Duchene). They sequenced MDV DNA from 15 ancient chickens, finding that these strains were basal to modern ones and identifying multiple fixed genetic changes. Testing the ancient version of the gene Meq, a regulator of tumor formation, the authors found that virulence was greatly reduced compared with modern versions. These results shed light on the evolution of virulence in a major disease in modern agriculture. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 321 |
| Topical term or geographic name entry element | arqueologia |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 117 |
| Topical term or geographic name entry element | fauna |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 501 |
| Topical term or geographic name entry element | ramaderia |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 422 |
| Topical term or geographic name entry element | biologia |
| 651 #0 - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME | |
| 9 (RLIN) | 102 |
| Geographic name | Castell de Montsoriu |
| 773 ## - HOST ITEM ENTRY | |
| Parts relacionades | Vol 382, Issue 6676 (14 Dec. 2023) pp. 1276-1281 |
| Títol font | Science |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | https://www.science.org/doi/10.1126/science.adg2238 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | https://www.uab.cat/web/newsroom/news-detail/-1345830290613.html?detid=1345904691951&utm_source=miragenews&utm_medium=miragenews&utm_campaign=news |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Article |
| Suppress in OPAC | Públic |
| Expurgat | Exemplar perdut | Source of classification or shelving scheme | Estat de conservació de l'exemplar | Exclòs de préstec | Format de l'exemplar | Biblioteca propietària de l'exemplar | Localització actual exemplar | Data d'adquisició | Origen de l'adquisició | Total Checkouts | Codi de barres | Date last seen | URL | Price effective from | Koha item type |
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| Universal Decimal Classification | Digital | Centre de Documentació del Parc Natural del Montseny. Secció Humanitats | Centre de Documentació del Parc Natural del Montseny. Secció Humanitats | 18.12.2023 | Donació | CDMSY-ARB23120018 | 18.12.2023 | https://www.science.org/doi/10.1126/science.adg2238 | 18.12.2023 | Article |